If your gonna ship something that makes a ton of noise like a 50ml helios or a bunch of bac water, liquid orals,etc.. I recommened you put in a standard priority box or a box of similar size and then put it in the priority bag
http://www.fpm.iastate.edu/postal_pa.../USPS_EP14.jpg

No matter how tightly you pack it, some stuff just is sooooo obvious when you shake the box a little. Its rare but if a carrier happend to shake the box a little or maybe is inspecting someone on the box its quite obvious it can seem like a lot of liquid and that gives them probable cause to open the pack. Try putting in a box and then a bag. The bag doesnt help with the noise but it distracts the chance of shaking it. Its treated more as a bulk object. By nature the carriers will pick it up with 2 hands and it will distract the chance of hearing anything.