Reported Characteristics:
  • Chemical Structure:
  • Cutting/Bulking:N/A
  • Anabolic Rating:N/A
  • Active LIfe:1 day
  • Drug Class:Aromatase Inhibitor
  • Average Reccomended Dose:20mgs/day
  • Acne:No
  • Water Retention:No
  • High Blood Pressure:No
  • Decreases HPTA Function: NO. (Increases it)
  • Aromatization:NO (Inhibits it)
  • Liver Toxicity:No.
  • DHT Conversion:No
  • Average Price:
Exemestane is an Aromatase Inhibitor (often called an "AI"), which isthe name given to a broad class of drugs whose effect is to limit the conversion of testosterone via the aromatase enzyme into estrogen. Aromasin is very unique product, as it is whats known as a "steroidal suicide aromatase inhibitor," which means that it exerts its effects by blocking the enzyme responsible for the synthesization of estrogen from testosterone. It exerts this effect in an irreversible manner. This accounts for why it is called a "Suicidal Aromatase Inhibitor." Estrogen is responsible for many of the unwanted side effects atributed to steroids, including but not limited to water retention, acne, gynocomastia (development of breast tissue) and suppression of endogenous testosterone. Exemestane, possibly by eliminating estrogen's suppressive effects on the HPTA, also has the added benefit of boosting the users endogenous (natural) testosterone levels.
It is possible that the rise in endogenous levels of testosterone that exemestane causes could be unwanted by female athletes, because of possible virilizing effects. This is, however, highly unlikely. Exemestane exerts it's effects, at the reccomended dose, to a greater degree than most other commonly used Aromatase Inhibitors (it boasts an 85% rate of estrogen suppression). What makes Exemestane especially noteworthy is that usually a decrease in estrogen levels is positively correlated with a decrease in the anabolic hormone Insulin-Like Growth Factor-1 (IGF-1), and has a negative impact on blood lipid profiles (cholesterol). Exemestane seems to not only increase IGF-1, but it has a positive effect on cholesterol.
Athletes who have reported using exemestane have found that 20mgs/day was enough to eliminate the water retention often experienced on heavy androgen cycles, as well as provide a slight anabolic ffect, probably due to the increase in IGF-1 and endogenous testosterone levels it provides.